XIX International AIDS Conference


MOSA17 HIV and Aging: A Global Perspective on Research, Care and Prevention
  Non-Commercial Satellite
Venue: Session Room 6
Time: 23.07.2012, 18:30 - 20:30
Co-Chairs: Alan Landay, United States
Kevin High, United States
Organiser: Alan Landay, Rush University Medical Center; Kevin High, Wake Forest School of Medicine; Amy Justice, Yale University; Paolo G. Miotti, National Institutes of Health and, EJ Beck, UNAIDS
 
 
The satellite Symposium has the goal of integrating topics in the area of "HIV and Aging", including research, clinical care and socio-behavioral aspects. The Symposium will define gaps in knowledge and point to directions in how to translate scientific findings into strategies for optimum service provision, within local socio-economic and cultural context, for older people living with HIV and those affected by HIV. The Symposium will cover discrete areas that will give the audience a global perspective on research, care and prevention. Topics will include regional differences in prevalence and incidence of HIV in older adults, new and evolving challenges in biomedical research, integration of clinical care for individuals aging with HIV, and socio-behavioral issues for such individuals. A panel discussion will follow with people living with HIV, researchers, clinicians and policy makers.

18:30
Welcome by Chairs


A. Landay, United States
K. High, United States

18:35
Global Prevalence and Incidence of HIV Infection Among Older Adults: Regional and Sex Differences


E. Beck, Switzerland

18:55

Powerpoint
Overview and Structure of the OAR Report on HIV and Aging


P. Volberding, United States

19:00

Powerpoint
Premature Aging and Functional Decline Associated with HIV Disease: Mechanisms and Triggers


R. Effros, United States

19:20

Powerpoint
Optimizing Health Care in the Context of Multimorbidity, Polypharmacy, and Decreasing Physiologic Reserve


A. Justice, United States

19:40

Powerpoint
Socio-behavioral Issues in Aging and HIV: Critical for Success in Prevention and Care


S. Deren, United States

20:00

Powerpoint
Panel Discussion of People Living with HIV, Researchers, Clinicians and Policy Makers


J. Negin, Australia
M. Sachikonye, United Kingdom
M. Saag, United States
F. Abdullah, South Africa
D. Ochieng, Kenya
A. Avihingsanon, Thailand

Powerpoints presentations
Overview and Structure of the OAR Report on HIV and Aging - Paul Volberding

Premature Aging and Functional Decline Associated with HIV Disease: Mechanisms and Triggers - Rita Effros

Optimizing Health Care in the Context of Multimorbidity, Polypharmacy, and Decreasing Physiologic Reserve - Amy Justice

Socio-behavioral Issues in Aging and HIV: Critical for Success in Prevention and Care - Sherry Deren

Panel Discussion of People Living with HIV, Researchers, Clinicians and Policy Makers -



Rapporteur reports

Track B report by Dr. John McKinnon


1. Global Prevalence and Incidence of HIV Infection Among Older Adults: Regional and Sex Differences, by Eduard Beck.
Conclusion: Increased overall prevalence and incidence of HIV infection in men and women over 50 y.o. This leads to significant national policy implications and increased need for directed research.
Action: Increased need for integration of services both HIV and non-communicable diseases, including Geriatric care.
2. Overview and Structure of the OAR Report on HIV and Aging, by Paul Volberding
Task was divided in 4 groups including: a. Mechanisms triggering functional decline, b. Biomarkers and clinical predictors, c. Aging with HIV infection, d. Societal infrastructure. This required a multidisciplinary team tackling each area. Description of the structure of OAR which was followed in the presentations to follow.

3. Premature Aging and Functional Delcine Associated with HIV Disease: Mechanisms and Triggers. By Rita Effros.
Conclusion: Immune system aging by senescent T cells and loss of telomere length due to chronic immune activation in HIV disease play a role, which is seen also in bone and cardiovascular disease.
Action: Important to keep a global perspective as markers identified in one population may not be relevant across diverse patient populations, and will require further validation and study.

4. Optimizing Health Care in the Context of Multimorbidity, Polypharmacy and Decreasing Physiologic Reserve, by Amy C. Justice.
Conclusions: HIV disease in the PLHIV over 50 y.o. does not occur in a vacuum and there are several other diseases, polypharmacy and comorbid conditions impacting care. The VACS Index is a new tool to assess the overall impact of all these conditions on patient’s health.
Action: Need for a map to optimize care for PLHIV over 50yo and multiple comorbidities. Newer tools to assess functional decline, especially subtle changes are needed, and better health risk assessments.

5. Socio-behavioral Issues in Aging and HIV: Critical for Success in Prevention and Care, by Sherry Deren
Conclusion: Multilevel factors are involved in impacting HIV care in the aging population and will require a multidisciplinary team for both care and research. Important that these factors are contextual and will vary by region.
Action: Research is needed to evaluate all key research areas affecting socio-behavioral issues.

6. Panel Discussion & Questions:
a. Most pressing factor concerns for those aging with HIV: Neglect, long term medication side effects, sexuality, neurocognitive decline, financial, long term care.
b. Most important comorbid conditions in this population: Not enough research in the area, general medicine issues, menopause, neurocognitive decline
c. Which comorbidities can be most readily prevented and or treated: Frailty
d. Main barriers for this population: Palliative care, access to care, stigma, losing hope and fear

Session: Discussed the expansion of the PLHIV over 50 yo, and the significant challenges that lay ahead in evaluation the interaction of HIV with aging, and what will be needed to provide better care of this population.


CPC report by Memory Sachikonye


The  session was on integrating topics in the area of HIV and Ageing, including research, clinical care and socio-behavioral aspects. The session examined gaps in knowledge and indicated directions in how to translate scientific findings into strategies for optimum service provision, within local socio-economic and cultural context, for older people living with HIV and those affected by HIV.

Topics included regional differences in prevalence and incidence of HIV in older adults, new and evolving challenges in biomedical research, integration of clinical care for individuals aging with HIV, and socio-behavioral issues for such individuals. An international panel discussion followed with people living with HIV, researchers, clinicians and policy makers.

To optimize healthcare, the following gaps should be addressed:

·         HIV complications leading to non-adherence and co-infections.

·         Lack of coordinated communication between HIV and non-HIV services, better linkages between institutions.

·         Poly-pharmacy can be more harmful than good; HCPs should only prescribe what is needed.

·         HIV and testing programmes for older people.

·         Clinicians should be aware of the needs of older HIV patients.

·         More research focusing on medical and physco-social issues in older HIV patients.

Socio-behavioral issues:

·         Individual, behavioral – substance use, mental health and cognitive impairment

·         Social – networks and support, stigma and ageism.

·         Structural – syringe exchange programmes, barrier to accessing services.

The session called for necessary linkages with the national policy and integrated HIV services.  There are common challenges with other chronic conditions and this has a policy implication. HIV services should be linked to co-morbid specialist services such as CVD, renal, etc.   Multidisciplinary teams need education in social issues with biomedical and behavioral expertise.

 




   

    The organizers reserve the right to amend the programme.


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