“Communicating Complex Science in a 140 Characters: Social Media and the HIV Prevention Research Field” discussed how the Internet is a tool for HIV prevention, focusing on the role of social networking sites. The National Black Gay Men’s Advocacy coalition described how a survey they conducted on how information channels are used among black, gay men in the United States confirmed their belief that the internet was crucial to communicating their messages. In order to receive information about advocacy and policy updates for HIV 59% of their respondents reported using e-mail, 56% said they used social networks, and 39% logged on to websites. Additionally 95% of respondents reported using Facebook new in their everyday life and 41% reported using Twitter. The International Rectal Microbicides Advocates attributed their success as an organization largely to social media, and gave tips on ways this technology to reach target audiences. They suggested keeping messages simple and to provide links instead of attempting to explain to more detailed, using attention-grabbing graphics, and balancing regular communications with subscribers without inundating them with too many messages. The HTVN 505, an HIV vaccine efficacy trial discussed the use of social media as necessary for recruitment in clinical trials. They reported that 31% of their participants had been recruited through social media platforms. Lastly, The Global Advocacy for HIV prevention explained how to better engaged in HIV advocacy issues through social media. They asserted that for HIV/AIDS advocates, social media was important not only for gaining access to peers and news sources, but also for understanding the viewpoints of those who disagree with their causes. The take-home message of this session was that social networking has become a fundamental part of American daily life, and therefore it is essential for HIV prevention organizations to integrate it into their communication strategy.